PPARα agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibitio...
PPARα agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
About this item
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Author / Creator
Publisher
National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
National Academy of Sciences
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Scope and Contents
Contents
Angiogenesis and inflammation are central processes through which the tumor microenvironment influences tumor growth. We have demonstrated recently that peroxisome proliferator-activated receptor (PPAR)α deficiency in the host leads to overt inflammation that suppresses angiogenesis via excess production of thrombospondin (TSP)-1 and prevents tumor...
Alternative Titles
Full title
PPARα agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
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Record Identifier
TN_cdi_jstor_primary_25451208
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25451208
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0711281105
