ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and...
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way
About this item
Full title
Author / Creator
Publisher
National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
IL-1β and IL-18 are crucial mediators of inflammation, and a defective control of their release may cause serious diseases. Yet, the mechanisms regulating IL-1β and IL-18 secretion are partially undefined. Both cytokines are produced as inactive cytoplasmic precursors. Processing to the active form is mediated by caspase-1, which is in turn activat...
Alternative Titles
Full title
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_25462732
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25462732
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0709684105
