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Activation of P2X7 Receptors in Glial Satellite Cells Reduces Pain through Downregulation of P2X3 Re...

Activation of P2X7 Receptors in Glial Satellite Cells Reduces Pain through Downregulation of P2X3 Re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25465170

Activation of P2X7 Receptors in Glial Satellite Cells Reduces Pain through Downregulation of P2X3 Receptors in Nociceptive Neurons

About this item

Full title

Activation of P2X7 Receptors in Glial Satellite Cells Reduces Pain through Downregulation of P2X3 Receptors in Nociceptive Neurons

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (43), p.16773-16778

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Purinergic ionotropic P2X7 receptors (P2X7Rs) are closely associated with excitotoxicity and nociception. Inhibition of P2X7R activation has been considered as a potentially useful strategy to improve recovery from spinal cord injury and reduce inflammatory damage to trauma. The physiological functions of P2X7Rs, however, are poorly understood, eve...

Alternative Titles

Full title

Activation of P2X7 Receptors in Glial Satellite Cells Reduces Pain through Downregulation of P2X3 Receptors in Nociceptive Neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25465170

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25465170

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0801793105

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