T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfβ2 expression and en...
T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfβ2 expression and endocardial cushion formation
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National Academy of Sciences
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English
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National Academy of Sciences
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During early heart development, Tbx2 gene expression is initiated in the cardiac crescent and then becomes restricted to the outflow tract and the atrioventricular region. We identified a Tbx2 regulatory region, enriched in multiple Smad sites, sufficient to reproduce Tbx2 expression patterns overlapping Bmp2 and Bmp4 gene activity in the heart. Th...
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T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfβ2 expression and endocardial cushion formation
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TN_cdi_jstor_primary_25593059
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25593059
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0900635106