Crystal structure of HLA-DP2 and implications for chronic beryllium disease
Crystal structure of HLA-DP2 and implications for chronic beryllium disease
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Chronic beryllium disease (CBD) is a fibrotic lung disorder caused by beryllium (Be) exposure and is characterized by granulomatous inflammation and the accumulation of Be-responsive CD4⁺ T cells in the lung. Genetic susceptibility to CBD has been associated with certain alleles of the MHCII molecule HLA-DP, especially HLA-DPB1*0201 and other allel...
Alternative Titles
Full title
Crystal structure of HLA-DP2 and implications for chronic beryllium disease
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TN_cdi_jstor_primary_25665369
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25665369
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1001772107
