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WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled...

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25681802

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

About this item

Full title

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (23), p.10442-10447

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

We recently showed that the Wiskott-Aldrich syndrome protein (WASP) family member, WASH, localizes to endosomal subdomains and regulates endocytic vesicle scission in an Arp2/3-dependent manner. Mechanisms regulating WASH activity are unknown. Here we show that WASH functions in cells within a 500 kDa core complex containing Strumpellin, FAM21, KIA...

Alternative Titles

Full title

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25681802

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25681802

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0913293107

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