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Pathology tissue—chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the...

Pathology tissue—chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25756919

Pathology tissue—chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples

About this item

Full title

Pathology tissue—chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21535-21540

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Epigenetic alterations in the pattern of DNA and histone modifications play a crucial role in cancer development. Analysis of patient samples, however, is hampered by technical limitations in the study of chromatin structure from pathology archives that usually consist of heavily fixed, paraffin-embedded material. Here, we present a methodology [pa...

Alternative Titles

Full title

Pathology tissue—chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25756919

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25756919

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1007647107

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