Postsynaptic P/Q-type Ca²⁺ channel in Purkinje cell mediates synaptic competition and elimination in...
Postsynaptic P/Q-type Ca²⁺ channel in Purkinje cell mediates synaptic competition and elimination in developing cerebellum
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Neural circuits are initially redundant but rearranged through activity-dependent synapse elimination during postnatal development. This process is crucial for shaping mature neural circuits and for proper brain function. At birth, Purkinje cells (PCs) in the cerebellum are innervated by multiple climbing fibers (CFs) with similar synaptic strength...
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Full title
Postsynaptic P/Q-type Ca²⁺ channel in Purkinje cell mediates synaptic competition and elimination in developing cerebellum
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Record Identifier
TN_cdi_jstor_primary_25831347
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25831347
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1101488108
