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An underlying mechanism for the increased mutagenesis of lagging-strand genes inBacillus subtilis

An underlying mechanism for the increased mutagenesis of lagging-strand genes inBacillus subtilis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26461792

An underlying mechanism for the increased mutagenesis of lagging-strand genes inBacillus subtilis

About this item

Full title

An underlying mechanism for the increased mutagenesis of lagging-strand genes inBacillus subtilis

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (10), p.E1096-E1105

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

We previously reported that lagging-strand genes accumulate mutations faster than those encoded on the leading strand inBacillus subtilis. Although we proposed that orientation-specific encounters between replication and transcription underlie this phenomenon, the mechanism leading to the increased mutagenesis of lagging-strand genes remained unkno...

Alternative Titles

Full title

An underlying mechanism for the increased mutagenesis of lagging-strand genes inBacillus subtilis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_26461792

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26461792

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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