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Microfluidic screening and whole-genome sequencing identifies mutations associated with improved pro...

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved pro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26464051

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast

About this item

Full title

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.E4689-E4696

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

There is an increasing demand for biotech-based production of recombinant proteins for use as pharmaceuticals in the food and feed industry and in industrial applications. YeastSaccharomyces cerevisiaeis among preferred cell factories for recombinant protein production, and there is increasing interest in improving its protein secretion capacity. D...

Alternative Titles

Full title

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_26464051

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26464051

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1506460112