Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological str...
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart
About this item
Full title
Author / Creator
Rasmussen, Tyler P , Yuejin Wu , Mei-ling A. Joiner , Olha M. Koval , Nicholas R. Wilson , Elizabeth D. Luczak , Qinchuan Wang , Biyi Chen , Zhan Gao , Zhiyong Zhu , Brett A. Wagner , Jamie Soto , Michael L. McCormick , William Kutschke , Robert M. Weiss , Liping Yu , Ryan L. Boudreau , E. Dale Abel , Fenghuang Zhan , Douglas R. Spitz , Garry R. Buettner , Long-Sheng Song , Leonid V. Zingman and Mark E. Anderson
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Myocardial mitochondrial Ca ²⺠entry enables physiological stress responses but in excess promotes injury and death. However, tissue-specific in vivo systems for testing the role of mitochondrial Ca ²⺠are lacking. We developed a mouse model with myocardial delimited transgenic expression of a dominant negative (DN) form of the mitochondrial...
Alternative Titles
Full title
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart
Authors, Artists and Contributors
Author / Creator
Yuejin Wu
Mei-ling A. Joiner
Olha M. Koval
Nicholas R. Wilson
Elizabeth D. Luczak
Qinchuan Wang
Biyi Chen
Zhan Gao
Zhiyong Zhu
Brett A. Wagner
Jamie Soto
Michael L. McCormick
William Kutschke
Robert M. Weiss
Liping Yu
Ryan L. Boudreau
E. Dale Abel
Fenghuang Zhan
Douglas R. Spitz
Garry R. Buettner
Long-Sheng Song
Leonid V. Zingman
Mark E. Anderson
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_26466121
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26466121
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1504705112
