Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional...
Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways
About this item
Full title
Author / Creator
Kirkby, Nicholas S. , Chan, Melissa V. , Zaiss, Anne K. , Garcia-Vaz, Eliana , Jiao, Jing , Berglund, Lisa M. , Verdu, Elena F. , Ahmetaj-Shala, Blerina , Wallace, John L. , Herschman, Harvey R. , Gomez, Maria F. , Mitchell, Jane A. , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , Department of Experimental Medical Science , Cardiovascular Research - Immunity and Atherosclerosis , Kärlfysiologi , Kardiovaskulär forskning - immunitet och ateroskleros , Institutionen för kliniska vetenskaper, Malmö , Diabetiska komplikationer , Strategic research areas (SRA) , Vascular Physiology , Lunds universitet , Profilområden och andra starka forskningsmiljöer , Lund University , EXODIAB: Excellence of Diabetes Research in Sweden , Institutionen för experimentell medicinsk vetenskap , Profile areas and other strong research environments , Diabetic Complications and Department of Clinical Sciences, Malmö
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Cyclooxygenase-2 (COX-2) is an inducible enzyme that drives inflammation and is the therapeutic target for widely used nonsteroidal antiinflammatory drugs (NSAIDs). However, COX-2 is also constitutively expressed, in the absence of overt inflammation, with a specific tissue distribution that includes the kidney, gastrointestinal tract, brain, and t...
Alternative Titles
Full title
Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways
Authors, Artists and Contributors
Author / Creator
Chan, Melissa V.
Zaiss, Anne K.
Garcia-Vaz, Eliana
Jiao, Jing
Berglund, Lisa M.
Verdu, Elena F.
Ahmetaj-Shala, Blerina
Wallace, John L.
Herschman, Harvey R.
Gomez, Maria F.
Mitchell, Jane A.
Faculty of Medicine
Medicinska fakulteten
Strategiska forskningsområden (SFO)
Department of Experimental Medical Science
Cardiovascular Research - Immunity and Atherosclerosis
Kärlfysiologi
Kardiovaskulär forskning - immunitet och ateroskleros
Institutionen för kliniska vetenskaper, Malmö
Diabetiska komplikationer
Strategic research areas (SRA)
Vascular Physiology
Lunds universitet
Profilområden och andra starka forskningsmiljöer
Lund University
EXODIAB: Excellence of Diabetes Research in Sweden
Institutionen för experimentell medicinsk vetenskap
Profile areas and other strong research environments
Diabetic Complications
Department of Clinical Sciences, Malmö
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_26467376
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26467376
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1517642113
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