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Clusters of circulating tumor cells traverse capillary-sized vessels

Clusters of circulating tumor cells traverse capillary-sized vessels

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26469479

Clusters of circulating tumor cells traverse capillary-sized vessels

About this item

Full title

Clusters of circulating tumor cells traverse capillary-sized vessels

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (18), p.4947-4952

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Multicellular aggregates of circulating tumor cells (CTC clusters) are potent initiators of distant organ metastasis. However, it is currently assumed that CTC clusters are too large to pass through narrow vessels to reach these organs. Here, we present evidence that challenges this assumption through the use of microfluidic devices designed to mim...

Alternative Titles

Full title

Clusters of circulating tumor cells traverse capillary-sized vessels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_26469479

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26469479

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1524448113

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