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Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a...

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26933248

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels

About this item

Full title

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels

Publisher

Royal Society

Journal title

Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 2020-06, Vol.378 (2173), p.1-20

Language

English

Formats

Publication information

Publisher

Royal Society

More information

Scope and Contents

Contents

Delayed afterdepolarizations (DADs) and spontaneous depolarizations (SDs) are typically triggered by spontaneous diastolic Ca2+ release from the sarcoplasmic reticulum (SR) which is caused by an elevated SR Ca2+-ATPase (SERCA) uptake and dysfunctional ryanodine receptors. However, recent studies on the T-box transcription factor gene (TBX5) demonst...

Alternative Titles

Full title

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_26933248

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26933248

Other Identifiers

ISSN

1364-503X

E-ISSN

1471-2962

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