Compartmentalization of Protein Kinase a Signaling by the Heterotrimeric G Protein$G_{o}
Compartmentalization of Protein Kinase a Signaling by the Heterotrimeric G Protein$G_{o}
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National Academy of Sciences
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English
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National Academy of Sciences
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$G_{o}$, a member of the $G_{o/i}$ family, is the most abundant heterotrimeric G protein in brain. Most functions of $G_{o}$ are mediated by the $G_{\beta\gamma}$ dimer; effector(s) for its α-subunit have not been clearly defined. Here we report that $G_{o\alpha}$ interacts directly with cAMP-dependent protein kinase (PKA) through its GTPase domain...
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Full title
Compartmentalization of Protein Kinase a Signaling by the Heterotrimeric G Protein$G_{o}
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TN_cdi_jstor_primary_30051263
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_30051263
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ISSN
0027-8424
DOI
10.1073/pnas.0609392103
