Log in to save to my catalogue

uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues

uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_30052437

uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues

About this item

Full title

uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (46), p.17361-17365

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Overexpression of urokinase plasminogen activator system or HER-2 (erbB-2) in breast cancer is associated with a poor prognosis. HER-2 overexpression is caused by HER-2 gene amplification. The anti-HER-2 antibody trastuzumab significantly improves clinical outcome for HER2-positive breast cancer. Drugs that target the uPA system are in early clinic...

Alternative Titles

Full title

uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_30052437

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_30052437

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0608113103

How to access this item