uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues
uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues
About this item
Full title
Author / Creator
Meng, Songdong , Tripathy, Debu , Shete, Sanjay , Ashfaq, Raheela , Saboorian, Hossein , Haley, Barbara , Frenkel, Eugene , Euhus, David , Leitch, Marilyn , Osborne, Cynthia , Clifford, Edward , Perkins, Steve , Beitsch, Peter , Khan, Amanullah , Morrison, Larry , Herlyn, Dorothee , Terstappen, Leon W. M. M. , Lane, Nancy , Wang, Jianqiang and Uhr, Jonathan
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Overexpression of urokinase plasminogen activator system or HER-2 (erbB-2) in breast cancer is associated with a poor prognosis. HER-2 overexpression is caused by HER-2 gene amplification. The anti-HER-2 antibody trastuzumab significantly improves clinical outcome for HER2-positive breast cancer. Drugs that target the uPA system are in early clinic...
Alternative Titles
Full title
uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues
Authors, Artists and Contributors
Author / Creator
Tripathy, Debu
Shete, Sanjay
Ashfaq, Raheela
Saboorian, Hossein
Haley, Barbara
Frenkel, Eugene
Euhus, David
Leitch, Marilyn
Osborne, Cynthia
Clifford, Edward
Perkins, Steve
Beitsch, Peter
Khan, Amanullah
Morrison, Larry
Herlyn, Dorothee
Terstappen, Leon W. M. M.
Lane, Nancy
Wang, Jianqiang
Uhr, Jonathan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_30052437
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_30052437
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0608113103