Evidence for a Cytopathogenicity Determinant in HIV-1 Vpr
Evidence for a Cytopathogenicity Determinant in HIV-1 Vpr
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
HIV-1 is cytopathic for CD4+ T lymphocytes in vitro and this property of HIV-1 is generally considered to account for some of its in vivo cytopathogenicity. Thus, the extent of lymphocyte depletion correlates with the level of viremia whereas low levels of viral replication are typically associated with stable lymphocyte levels and asymptomatic inf...
Alternative Titles
Full title
Evidence for a Cytopathogenicity Determinant in HIV-1 Vpr
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TN_cdi_jstor_primary_3059228
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3059228
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.142313699