Cell Spreading Controls Endoplasmic and Nuclear Calcium: A Physical Gene Regulation Pathway from the...
Cell Spreading Controls Endoplasmic and Nuclear Calcium: A Physical Gene Regulation Pathway from the Cell Surface to the Nucleus
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Cells attaching to an extracellular matrix through integrins flatten out (spread) on the matrix, eliciting cellular signals needed for survival. We show that the shape of the nucleus changes and the nuclear calcium level increases in spreading cells. Moreover, cell spreading and osmotic stretching of isolated nuclei cause release of perinuclear Ca2...
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Full title
Cell Spreading Controls Endoplasmic and Nuclear Calcium: A Physical Gene Regulation Pathway from the Cell Surface to the Nucleus
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TN_cdi_jstor_primary_3139686
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3139686
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0531397100
