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IL-17 Production from Activated T Cells Is Required for the Spontaneous Development of Destructive A...

IL-17 Production from Activated T Cells Is Required for the Spontaneous Development of Destructive A...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3147529

IL-17 Production from Activated T Cells Is Required for the Spontaneous Development of Destructive Arthritis in Mice Deficient in IL-1 Receptor Antagonist

About this item

Full title

IL-17 Production from Activated T Cells Is Required for the Spontaneous Development of Destructive Arthritis in Mice Deficient in IL-1 Receptor Antagonist

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2003-05, Vol.100 (10), p.5986-5990

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

IL-17 is a T cell-derived, proinflammatory cytokine that is suspected to be involved in the development of various inflammatory diseases. Although there are elevated levels of IL-17 in synovial fluid of patients with rheumatoid arthritis, the pathogenic role of IL-17 in the development of rheumatoid arthritis remains to be elucidated. In this repor...

Alternative Titles

Full title

IL-17 Production from Activated T Cells Is Required for the Spontaneous Development of Destructive Arthritis in Mice Deficient in IL-1 Receptor Antagonist

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_3147529

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3147529

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1035999100

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