Regulation of Dopaminergic Transmission and Cocaine Reward by the Clock Gene
Regulation of Dopaminergic Transmission and Cocaine Reward by the Clock Gene
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Although there are clear interactions between circadian rhythms and drug addiction, mechanisms for such interactions remain unknown. Here we establish a role for the Clock gene in regulating the brain's reward circuit. Mice lacking a functional Clock gene display an increase in cocaine reward and in the excitability of dopamine neurons in the midbr...
Alternative Titles
Full title
Regulation of Dopaminergic Transmission and Cocaine Reward by the Clock Gene
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Record Identifier
TN_cdi_jstor_primary_3375903
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_3375903
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0503584102
