Experimental characterization of disordered and ordered aggregates populated during the process of a...
Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Recent experimental evidence points to intermediates populated during the process of amyloid fibril formation as the toxic moieties primarily responsible for the development of increasingly common disorders such as Alzheimer's disease and type II diabetes. We describe here the application of a pulse-labeling hydrogen-deuterium (HD) exchange strateg...
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Full title
Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation
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TN_cdi_jstor_primary_40482857
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40482857
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0812227106