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Experimental characterization of disordered and ordered aggregates populated during the process of a...

Experimental characterization of disordered and ordered aggregates populated during the process of a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40482857

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation

About this item

Full title

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (19), p.7828-7833

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Recent experimental evidence points to intermediates populated during the process of amyloid fibril formation as the toxic moieties primarily responsible for the development of increasingly common disorders such as Alzheimer's disease and type II diabetes. We describe here the application of a pulse-labeling hydrogen-deuterium (HD) exchange strateg...

Alternative Titles

Full title

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_40482857

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40482857

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0812227106

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