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Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain sti...

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain sti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40485087

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation

About this item

Full title

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16451-16456

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Peripheral interactions between nociceptive fibers and mast cells contribute to inflammatory pain, but little is known about mechanisms mediating neuro-immune communication. Here we show that metalloproteinase MT5-MMP (MMP-24) is an essential mediator of peripheral thermal nociception and inflammatory hyperalgesia. We report that MT5-MMP is express...

Alternative Titles

Full title

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_40485087

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40485087

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.0908507106

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