MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation...
MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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MYCN, a proto-oncogene normally expressed in the migrating neural crest, is in its amplified state a key factor in the genesis of human neuroblastoma (NB). However, the mechanisms underlying MYCN-mediated NB progression are poorly understood. Here, we present a MYCN-induced miRNA signature in human NB involving the activation and transrepression of...
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MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma
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TN_cdi_jstor_primary_40536366
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40536366
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.0913517107
