Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane su...
Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The recognition and binding of cholesterol is an important feature of many eukaryotic, viral, and prokaryotic proteins, but the molecular details of such interactions are understood only for a few proteins. The pore-forming cholesterol-dependent cytolysins (CDCs) contribute to the pathogenic mechanisms of a large number of Gram-positive bacteria. C...
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Full title
Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface
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TN_cdi_jstor_primary_40537126
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40537126
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0911581107