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Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane su...

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane su...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40537126

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

About this item

Full title

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4341-4346

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The recognition and binding of cholesterol is an important feature of many eukaryotic, viral, and prokaryotic proteins, but the molecular details of such interactions are understood only for a few proteins. The pore-forming cholesterol-dependent cytolysins (CDCs) contribute to the pathogenic mechanisms of a large number of Gram-positive bacteria. C...

Alternative Titles

Full title

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_40537126

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_40537126

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0911581107

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