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AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maint...

AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maint...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_41352399

AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

About this item

Full title

AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (38), p.16092-16097

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

AMP-activated protein kinase (AMPK) β1 or β2 subunits are required for assembling of AMPK heterotrimers and are important for regulating enzyme activity and cellular localization. In skeletal muscle, α2β2γ3-containing heterotrimers predominate. However, compensatory up-regulation and redundancy of AMPK subunits in whole-body AMPK α2, β2, and γ3 nul...

Alternative Titles

Full title

AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_41352399

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_41352399

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1105062108

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