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Brush border Myosin la has tumor suppressor activity in the intestine

Brush border Myosin la has tumor suppressor activity in the intestine

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_41477133

Brush border Myosin la has tumor suppressor activity in the intestine

About this item

Full title

Brush border Myosin la has tumor suppressor activity in the intestine

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (5), p.1530-1535

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

The loss of the epithelial architecture and cell polarity/differentiation is known to be important during the tumorigenic process. Here we demonstrate that the brush border protein Myosin la (MYO1A) is important for polarization and differentiation of colon cancer cells and is frequently inactivated in colorectal tumors by genetic and epigenetic me...

Alternative Titles

Full title

Brush border Myosin la has tumor suppressor activity in the intestine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_41477133

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_41477133

Other Identifiers

ISSN

0027-8424

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