Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids
Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Staphylococcus aureus peptidoglycan (PG) is densely functionalized with anionic polymers called wall teichoic acids (WTAs). These polymers contain three tailoring modifications: d -alanylation, α- O -GlcNAcylation, and β- O -GlcNAcylation. Here we describe the discovery and biochemical characterization of a unique glycosyltransferase, TarS, that at...
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Full title
Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids
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TN_cdi_jstor_primary_41830124
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_41830124
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1209126109
