mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair...
mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The gene causative for the human nonsyndromic recessive form of deafness DFNB22 encodes otoancorin, a 120-kDa inner ear-specific protein that is expressed on the surface of the spiral limbus in the cochlea. Gene targeting in ES cells was used to create an EGFP knock-in, otoancorin KO (Otoa ᴱᴳFᴾ/ᴱᴳFᴾ) mouse. In the Otoa ᴱᴳFᴾ/ᴱᴳFᴾ mouse, the tectoria...
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mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation
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TN_cdi_jstor_primary_41830212
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_41830212
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1210159109
