Mutation of the ATP-gated P2X₂ receptor leads to progressive hearing loss and increased susceptibili...
Mutation of the ATP-gated P2X₂ receptor leads to progressive hearing loss and increased susceptibility to noise
About this item
Full title
Author / Creator
Yan, Denise , Zhu, Yan , Walsh, Tom , Xie, Dinghua , Yuan, Huijun , Sirmaci, Asli , Fujikawa, Taro , Wong, Ann Chi Yan , Loh, Tze L. , Du, Lilin , Grati, M'hamed , Vlajkovic, Srdjan M. , Blanton, Susan , Ryan, Allen F. , Chen, Zheng-Yi , Thorne, Peter R. , Kachar, Bechara , Tekin, Mustafa , Zhao, Hong-Bo , Housley, Gary D. , King, Mary-Claire and Liu, Xue Z.
Publisher
National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Age-related hearing loss and noise-induced hearing loss are major causes of human morbidity. Here we used genetics and functional studies to show that a shared cause of these disorders may be loss of function of the ATP-gated P2X ₂ receptor (ligand-gated ion channel, purinergic receptor 2) that is expressed in sensory and supporting cells of the co...
Alternative Titles
Full title
Mutation of the ATP-gated P2X₂ receptor leads to progressive hearing loss and increased susceptibility to noise
Authors, Artists and Contributors
Author / Creator
Zhu, Yan
Walsh, Tom
Xie, Dinghua
Yuan, Huijun
Sirmaci, Asli
Fujikawa, Taro
Wong, Ann Chi Yan
Loh, Tze L.
Du, Lilin
Grati, M'hamed
Vlajkovic, Srdjan M.
Blanton, Susan
Ryan, Allen F.
Chen, Zheng-Yi
Thorne, Peter R.
Kachar, Bechara
Tekin, Mustafa
Zhao, Hong-Bo
Housley, Gary D.
King, Mary-Claire
Liu, Xue Z.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_41992208
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_41992208
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1222285110
