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Crucial role of the hydrophobie pocket region of Munc18 protein in mast cell degranulation

Crucial role of the hydrophobie pocket region of Munc18 protein in mast cell degranulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42583316

Crucial role of the hydrophobie pocket region of Munc18 protein in mast cell degranulation

About this item

Full title

Crucial role of the hydrophobie pocket region of Munc18 protein in mast cell degranulation

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (12), p.4610-4615

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

The function of the Munc18-1 protein hydrophobic pocket, which interacts with the syntaxin-1 N-terminal peptide, has been highly controversial in neurosecretion. Recent analysis of patients with familial hemophagocytic lymphohistiocytosis type 5 has identified the E132A mutation in the hydrophobic pocket of Munc18-2, prompting us to examine the rol...

Alternative Titles

Full title

Crucial role of the hydrophobie pocket region of Munc18 protein in mast cell degranulation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_42583316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42583316

Other Identifiers

ISSN

0027-8424

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