Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vasc...
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
About this item
Full title
Author / Creator
Kucharzewska, Paulina , Christianson, Helena C. , Welch, Johanna E. , Svensson, Katrin J. , Fredlund, Erik , Ringnér, Markus , Mörgelin, Matthias , Bourseau-Guilmain, Erika , Bengzon, Johan , Belting, Mattias , Strategiska forskningsområden (SFO) , Sektion III , Tumörmikromiljön , Bröstcancer-genetik , Section I , Strategic research areas (SRA) , Department of Clinical Sciences, Lund , Lund University , Profile areas and other strong research environments , Breastcancer-genetics , Tumor microenvironment , Infektionsmedicin , Faculty of Medicine , Medicinska fakulteten , StemTherapy: National Initiative on Stem Cells for Regenerative Therapy , Neurokirurgi , Institutionen för kliniska vetenskaper, Lund , Lunds universitet , Sektion I , Sektion IV , Tumörmikromiljö , Profilområden och andra starka forskningsmiljöer , Section IV , Section III , Neurosurgery and Infection Medicine (BMC)
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Hypoxia, or low oxygen tension, is a major regulator of tumor development and aggressiveness. However, how cancer cells adapt to hypoxia and communicate with their surrounding microenvironment during tumor development remain important questions. Here, we show that secreted vesicles with exosome characteristics mediate hypoxia-dependent intercellula...
Alternative Titles
Full title
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
Authors, Artists and Contributors
Author / Creator
Christianson, Helena C.
Welch, Johanna E.
Svensson, Katrin J.
Fredlund, Erik
Ringnér, Markus
Mörgelin, Matthias
Bourseau-Guilmain, Erika
Bengzon, Johan
Belting, Mattias
Strategiska forskningsområden (SFO)
Sektion III
Tumörmikromiljön
Bröstcancer-genetik
Section I
Strategic research areas (SRA)
Department of Clinical Sciences, Lund
Lund University
Profile areas and other strong research environments
Breastcancer-genetics
Tumor microenvironment
Infektionsmedicin
Faculty of Medicine
Medicinska fakulteten
StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
Neurokirurgi
Institutionen för kliniska vetenskaper, Lund
Lunds universitet
Sektion I
Sektion IV
Tumörmikromiljö
Profilområden och andra starka forskningsmiljöer
Section IV
Section III
Neurosurgery
Infection Medicine (BMC)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_jstor_primary_42590621
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42590621
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1220998110
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