Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors
Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The genetic and biophysical mechanisms by which new protein functions evolve is a central question in evolutionary biology, biochemistry, and biophysics. Of particular interest is whether major shifts in protein function are caused by a few mutations of large effect and, if they are, the mechanisms that mediate these changes. Here we combine ancest...
Alternative Titles
Full title
Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors
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Record Identifier
TN_cdi_jstor_primary_42712758
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_42712758
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1303930110
