Blood Pressure Reduction and Diabetes Insipidus in Transgenic Rats Deficient in Brain Angiotensinoge...
Blood Pressure Reduction and Diabetes Insipidus in Transgenic Rats Deficient in Brain Angiotensinogen
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United States: National Academy of Sciences of the United States of America
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Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
Angiotensin produced systemically or locally in tissues such as the brain plays an important role in the regulation of blood pressure and in the development of hypertension. We have established transgenic rats [TGR(ASrAOGEN)] expressing an antisense RNA against angiotensinogen mRNA specifically in the brain. In these animals, the brain angiotensino...
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Full title
Blood Pressure Reduction and Diabetes Insipidus in Transgenic Rats Deficient in Brain Angiotensinogen
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TN_cdi_jstor_primary_47749
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_47749
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.96.7.3975