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Inhibitory Effects of SU5416, a Selective Vascular Endothelial Growth Factor Receptor Tyrosine Kinas...

Inhibitory Effects of SU5416, a Selective Vascular Endothelial Growth Factor Receptor Tyrosine Kinas...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_324994

Inhibitory Effects of SU5416, a Selective Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, on Experimental Corneal Neovascularization

About this item

Full title

Inhibitory Effects of SU5416, a Selective Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, on Experimental Corneal Neovascularization

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Ophthalmic research, 2012-01, Vol.47 (1), p.13-18

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Purpose: Treatment of neovascularization in ocular diseases with vascular endothelial growth factor (VEGF) inhibition shows promising results. SU5416 is a low-molecular-weight tyrosine kinase inhibitor. It selectively inhibits the membrane-bound tyrosine kinase activity of VEGF-2 receptor (Flk-1/KDR) and blocks the intracellular signaling process....

Alternative Titles

Full title

Inhibitory Effects of SU5416, a Selective Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, on Experimental Corneal Neovascularization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_karger_primary_324994

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_324994

Other Identifiers

ISSN

0030-3747

E-ISSN

1423-0259

DOI

10.1159/000324994

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