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Tachyphylaxis to the Sumatriptan-Induced Contractile Effect in the Human Uterine Artery but Not in H...

Tachyphylaxis to the Sumatriptan-Induced Contractile Effect in the Human Uterine Artery but Not in H...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_334930

Tachyphylaxis to the Sumatriptan-Induced Contractile Effect in the Human Uterine Artery but Not in Human Cerebral Blood Vessels: Pharmacological Demonstration of the 5-HT1B Receptor Functionality Loss

About this item

Full title

Tachyphylaxis to the Sumatriptan-Induced Contractile Effect in the Human Uterine Artery but Not in Human Cerebral Blood Vessels: Pharmacological Demonstration of the 5-HT1B Receptor Functionality Loss

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Pharmacology, 2012-03, Vol.89 (1-2), p.29-36

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

The in vitro contractile response of the human uterine artery to sumatriptan was compared to that of human cerebral blood vessels. Artery rings were prepared for isometric contraction. Tachyphylaxis to the triptan-induced vascular contraction was observed in the uterine artery, but not in basilar and middle cerebral arteries. To evaluate 5-HT 1 rec...

Alternative Titles

Full title

Tachyphylaxis to the Sumatriptan-Induced Contractile Effect in the Human Uterine Artery but Not in Human Cerebral Blood Vessels: Pharmacological Demonstration of the 5-HT1B Receptor Functionality Loss

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_karger_primary_334930

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_334930

Other Identifiers

ISSN

0031-7012

E-ISSN

1423-0313

DOI

10.1159/000334930

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