Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarcti...
Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation
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Publisher
Basel, Switzerland: S. Karger AG
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Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Contents
Introduction: Methotrexate is a drug that has shown anti-ischemic effects in animal studies and positive results in heart failure clinical trials. Methods: We will randomly assign 80 patients with acute myocardial infarction to receive methotrexate (0.05 mg/kg bolus followed by 0.05 mg/kg/h for 6 h) or matching placebo. The primary outcome will be...
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Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation
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TN_cdi_karger_primary_351972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_351972
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ISSN
0008-6312
E-ISSN
1421-9751
DOI
10.1159/000351972