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Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarcti...

Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarcti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_351972

Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation

About this item

Full title

Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Cardiology, 2013-01, Vol.126 (3), p.167-170

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Introduction: Methotrexate is a drug that has shown anti-ischemic effects in animal studies and positive results in heart failure clinical trials. Methods: We will randomly assign 80 patients with acute myocardial infarction to receive methotrexate (0.05 mg/kg bolus followed by 0.05 mg/kg/h for 6 h) or matching placebo. The primary outcome will be...

Alternative Titles

Full title

Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_karger_primary_351972

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_351972

Other Identifiers

ISSN

0008-6312

E-ISSN

1421-9751

DOI

10.1159/000351972

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