Nucleus Pulposus Mesenchymal Stem Cells in Acidic Conditions Mimicking Degenerative Intervertebral D...
Nucleus Pulposus Mesenchymal Stem Cells in Acidic Conditions Mimicking Degenerative Intervertebral Discs Give Better Performance than Adipose Tissue-Derived Mesenchymal Stem Cells
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Author / Creator
Han, Bin , Wang, Hai-chao , Li, Hao , Tao, Yi-qing , Liang, Cheng-zhen , Li, Fang-cai , Chen, Gang and Chen, Qi-xin
Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publication information
Publisher
Basel, Switzerland: S. Karger AG
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Scope and Contents
Contents
The microenvironment of the intervertebral disc (IVD) is characterized by matrix acidity, hypoxia, hyperosmolarity and limited nutrition, which are major obstacles to stem cell-based regeneration. Our recent work showed that nucleus pulposus mesenchymal stem cells (NPMSCs) had advantages over traditional sources of cell therapy under IVD-like hypox...
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Full title
Nucleus Pulposus Mesenchymal Stem Cells in Acidic Conditions Mimicking Degenerative Intervertebral Discs Give Better Performance than Adipose Tissue-Derived Mesenchymal Stem Cells
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Author / Creator
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Record Identifier
TN_cdi_karger_primary_369452
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_369452
Other Identifiers
ISSN
1422-6405
E-ISSN
1422-6421
DOI
10.1159/000369452
