Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction
Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction
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Publisher
Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
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Language
English
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Publisher
Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
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Contents
Background/Aim: Plasma trimethylamine-N-oxide (TMAO), a product of intestinal microbial metabolism of dietary phosphatidylcholine has been recently associated with atherosclerosis and increased risk of cardiovascular diseases (CVD) in rodents and humans. However, the molecular mechanisms of how TMAO induces atherosclerosis and CVD progression are s...
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Full title
Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction
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TN_cdi_karger_primary_484623
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_484623
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ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000484623
