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Pterostilbene Reduces Acetaminophen-Induced Liver Injury by Activating the Nrf2 Antioxidative Defens...

Pterostilbene Reduces Acetaminophen-Induced Liver Injury by Activating the Nrf2 Antioxidative Defens...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_493655

Pterostilbene Reduces Acetaminophen-Induced Liver Injury by Activating the Nrf2 Antioxidative Defense System via the AMPK/Akt/GSK3β Pathway

About this item

Full title

Pterostilbene Reduces Acetaminophen-Induced Liver Injury by Activating the Nrf2 Antioxidative Defense System via the AMPK/Akt/GSK3β Pathway

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Cellular physiology and biochemistry, 2018-01, Vol.49 (5), p.1943-1958

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Background/Aims: Pterostilbene (Pts), a natural dimethylated analog of resveratrol from blueberries, exerts antioxidative and anti-apoptotic effects in various diseases. This study aims to investigate the protective effects and mechanism of Pts against acetaminophen (APAP)-induced hepatotoxicity in vivo. Methods: C57BL/6 mice were treated with APAP...

Alternative Titles

Full title

Pterostilbene Reduces Acetaminophen-Induced Liver Injury by Activating the Nrf2 Antioxidative Defense System via the AMPK/Akt/GSK3β Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_karger_primary_493655

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_karger_primary_493655

Other Identifiers

ISSN

1015-8987

E-ISSN

1421-9778

DOI

10.1159/000493655

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