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STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cel...

STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_kisti_ndsl_JAKO201606776009922

STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cells

About this item

Full title

STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cells

Journal title

Molecules and cells, 2016, Vol.39 (11), p.821-826

Language

Korean

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Scope and Contents

Contents

The ${\beta}$-catenin functions as an adhesion molecule and a component of the Wnt signaling pathway. In the absence of the Wnt ligand, ${\beta}$-catenin is constantly phosphorylated, which designates it for degradation by the APC complex. This process is one of the key regulatory mechanisms of ${\beta}$-catenin. The level of ${\beta}$-catenin is a...

Alternative Titles

Full title

STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_kisti_ndsl_JAKO201606776009922

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_kisti_ndsl_JAKO201606776009922

Other Identifiers

ISSN

1016-8478

E-ISSN

0219-1032

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