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Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTO...

Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTO...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrcresearch_primary_10_1139_bcb_2019_0333

Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway

About this item

Full title

Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

Journal title

Biochemistry and cell biology, 2020-05, Vol.98 (3), p.434-442

Language

English

Formats

Publication information

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

More information

Scope and Contents

Contents

Osteoarthritis (OA) is a common joint degenerative disease. Vitamin D (VD) is essential for bone health. We hypothesized that active VD could be used as a therapeutic treatment for OA. Low serum levels of 25-hydroxyvitamin D [25(OH)D] have been found in patients with OA, and thus the serum level of VD could be diagnostic of OA. To test this, we est...

Alternative Titles

Full title

Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_nrcresearch_primary_10_1139_bcb_2019_0333

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrcresearch_primary_10_1139_bcb_2019_0333

Other Identifiers

ISSN

0829-8211

E-ISSN

1208-6002

DOI

10.1139/bcb-2019-0333

How to access this item