Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTO...
Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway
About this item
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Author / Creator
Kong, Chunyu , Wang, Changlei , Shi, Yuquan , Yan, Lei , Xu, Junhua and Qi, Wufang
Publisher
1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press
Journal title
Language
English
Formats
Publication information
Publisher
1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press
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Scope and Contents
Contents
Osteoarthritis (OA) is a common joint degenerative disease. Vitamin D (VD) is essential for bone health. We hypothesized that active VD could be used as a therapeutic treatment for OA. Low serum levels of 25-hydroxyvitamin D [25(OH)D] have been found in patients with OA, and thus the serum level of VD could be diagnostic of OA. To test this, we est...
Alternative Titles
Full title
Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_nrcresearch_primary_10_1139_bcb_2019_0333
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrcresearch_primary_10_1139_bcb_2019_0333
Other Identifiers
ISSN
0829-8211
E-ISSN
1208-6002
DOI
10.1139/bcb-2019-0333