RUNX1 Upregulation Causes Mitochondrial Dysfunction via Regulating the PI3K-Akt Pathway in iPSC from...
RUNX1 Upregulation Causes Mitochondrial Dysfunction via Regulating the PI3K-Akt Pathway in iPSC from Patients with Down Syndrome
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Korean Society for Molecular and Cellular Biology
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Language
English
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Korean Society for Molecular and Cellular Biology
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Contents
Down syndrome (DS) is the most common autosomal aneuploidy caused by trisomy of chromosome 21. Previous studies demonstrated that DS affected mitochondrial functions, which may be associated with the abnormal development of the nervous system in patients with DS. Runt-related transcription factor 1 (RUNX1) is an encoding gene located on chromosome...
Alternative Titles
Full title
RUNX1 Upregulation Causes Mitochondrial Dysfunction via Regulating the PI3K-Akt Pathway in iPSC from Patients with Down Syndrome
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TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10225525
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10225525
Other Identifiers
ISSN
1016-8478
E-ISSN
0219-1032
DOI
10.14348/molcells.2023.2095
