PHGDH: a novel therapeutic target in cancer
PHGDH: a novel therapeutic target in cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Serine is a key contributor to the generation of one-carbon units for DNA synthesis during cellular proliferation. In addition, it plays a crucial role in the production of antioxidants that prevent abnormal proliferation and stress in cancer cells. In recent studies, the relationship between cancer metabolism and the serine biosynthesis pathway ha...
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Full title
PHGDH: a novel therapeutic target in cancer
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TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10585224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10585224
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ISSN
2092-6413,1226-3613
E-ISSN
2092-6413
DOI
10.1038/s12276-024-01268-1
