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Unique expression and critical role of metallothionein 3 in the control of osteoclastogenesis and os...

Unique expression and critical role of metallothionein 3 in the control of osteoclastogenesis and os...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10613588

Unique expression and critical role of metallothionein 3 in the control of osteoclastogenesis and osteoporosis

About this item

Full title

Unique expression and critical role of metallothionein 3 in the control of osteoclastogenesis and osteoporosis

Publisher

London: Nature Publishing Group UK

Journal title

Experimental and Molecular Medicine, 2024, 56(0), , pp.1791-1806

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Bone homeostasis is maintained by an intricate balance between osteoclasts and osteoblasts, which becomes disturbed in osteoporosis. Metallothioneins (MTs) are major contributors in cellular zinc regulation. However, the role of MTs in bone cell regulation has remained unexplored. Single-cell RNA sequencing analysis discovered that, unlike the expr...

Alternative Titles

Full title

Unique expression and critical role of metallothionein 3 in the control of osteoclastogenesis and osteoporosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10613588

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10613588

Other Identifiers

ISSN

2092-6413,1226-3613

E-ISSN

2092-6413

DOI

10.1038/s12276-024-01290-3

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