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MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the n...

MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the n...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10679260

MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the novel target Srpx2

About this item

Full title

MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the novel target Srpx2

Publisher

London: Nature Publishing Group UK

Journal title

Experimental and Molecular Medicine, 2025, 57(0), , pp.104-117

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Diabetes is an incurable, chronic disease that can lead to many complications, including angiopathy, peripheral neuropathy, and erectile dysfunction (ED). The angiopoietin-Tie2 signaling pathway plays a critical role in blood vessel development, formation, remodeling, and peripheral nerve regeneration. Therefore, strategies for activating the Tie2...

Alternative Titles

Full title

MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the novel target Srpx2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10679260

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10679260

Other Identifiers

ISSN

2092-6413,1226-3613

E-ISSN

2092-6413

DOI

10.1038/s12276-024-01373-1

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