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Rheumatoid arthritis severity is mediated by crosstalk between synoviocytes and mature osteoclasts t...

Rheumatoid arthritis severity is mediated by crosstalk between synoviocytes and mature osteoclasts t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10687672

Rheumatoid arthritis severity is mediated by crosstalk between synoviocytes and mature osteoclasts through a calcium and cytokine feedback loop

About this item

Full title

Rheumatoid arthritis severity is mediated by crosstalk between synoviocytes and mature osteoclasts through a calcium and cytokine feedback loop

Publisher

London: Nature Publishing Group UK

Journal title

Experimental and Molecular Medicine, 2025, 57(0), , pp.402-419

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fibroblast-like synoviocytes (FLSs) and osteoclasts are central cells in the maintenance of joint homeostasis. Rheumatoid arthritis (RA) is a chronic inflammatory disease of joints that induces cytokine-activated FLSs and progressive bone erosion. Interactions between FLSs and other cells, such as T cells and B cells, have been recognized in the de...

Alternative Titles

Full title

Rheumatoid arthritis severity is mediated by crosstalk between synoviocytes and mature osteoclasts through a calcium and cytokine feedback loop

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10687672

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_10687672

Other Identifiers

ISSN

2092-6413,1226-3613

E-ISSN

2092-6413

DOI

10.1038/s12276-025-01401-8

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