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CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_4151286

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

About this item

Full title

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

Publisher

London: Nature Publishing Group UK

Journal title

Experimental and Molecular Medicine, 2019, 51(0), , pp.1-15

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We identified principal genetic alterations in 97.1% (99/102) of patients with T-acute lymphoblastic leukemia (T-ALL) using integrative genetic analyses, including massive parallel sequencing and multiplex ligation-dependent probe amplification (MLPA). A total of 133 mutations were identified in the following genes in descending order:
NOTCH1

Alternative Titles

Full title

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_4151286

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_4151286

Other Identifiers

ISSN

1226-3613

E-ISSN

2092-6413

DOI

10.1038/s12276-018-0195-x

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