Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness...
Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness through the TGF-β1 pathway
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Prior studies have reported the presence of lung fibrosis and enhanced airway hyperresponsiveness (AHR) in mice with high-fat-diet (HFD)-induced obesity. This study evaluated the role of TGF-β1 in HFD-induced AHR and lung fibrosis in a murine model. We generated HFD-induced obesity mice and performed glucose and insulin tolerance tests. HFD mice wi...
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Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness through the TGF-β1 pathway
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TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_5485758
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_5485758
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ISSN
1226-3613,2092-6413
E-ISSN
2092-6413
DOI
10.1038/s12276-019-0258-7
