IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes
IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes
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Seoul: Springer Nature B.V
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Language
English
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Seoul: Springer Nature B.V
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Contents
Rheumatoid arthritis (RA) is an autoimmune disease characterized by persistent synovial inflammation. The major drivers of synovial inflammation are cytokines and chemokines. Among these molecules, TNF activates fibroblast-like synoviocytes (FLSs), which leads to the production of inflammatory mediators. Here, we show that TNF regulates the express...
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Full title
IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes
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TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_5916610
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_5916610
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ISSN
1226-3613
E-ISSN
2092-6413
DOI
10.1038/s12276-019-0267-6
