Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sour...
Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sources
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Publisher
England: BioMed Central
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Language
English
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England: BioMed Central
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Acetaminophen (APAP) is the most common antipyretic analgesic worldwide. However, APAP overdose causes severe liver injury, especially centrilobular necrosis, in humans and experimental animals. At therapeutic dosage, APAP is mainly metabolized by sulfation and glucuronidation, and partly by cytochrome P450-mediated oxidation. However, APAP overdos...
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Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sources
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TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_6171874
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_6171874
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ISSN
2233-7660,1738-6055
E-ISSN
2233-7660
DOI
10.1186/s42826-019-0017-x
